Macronissos is an island strongly disturbed by human activities. Seventeen species of land snails are distributed on the island. Subfossils found, show that the structure of the malacofauna has recently changed. The distribution of the species in the neighbouring areas does not show any special relation of Macronissos. Only the existence of Albinaria turrita on the island, is an indication of Macronissos’ closer relation to the Cyclades than to the mainland.